C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12N 5/12 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2471924
The present invention provides BAG3 nucleotide and protein sequences to be used in research, diagnostics and therapy for modulation of cell survival and/or death, in particular in leukemias, other neoplasias and apoptosis- involving diseases. More particularly the invention refers to the use of specific antisense~-based constructs and peptide-specific polyclonal and monoclonal antibodies in leukemias, other neoplasias and cell death- involving diseases.
L'invention concerne des séquences de protéines et de nucléotides BAG3 à utiliser dans la recherche, le diagnostic et le traitement à des fins de modulation de survie et/ou de mort cellulaire, en particulier dans des leucémies, d'autres néoplasies et des maladies impliquant l'apoptose. Plus particulièrement, l'invention concerne l'utilisation de constructions à base d'antisens spécifiques et d'anticorps polyclonaux et monoclonaux spécifiques des peptides dans des leucémies, d'autres néoplasies et des maladies impliquant la mort cellulaire.
Leone Arturo
Turco Maria Caterina
Biouniversa S.r.l.
Leone Arturo
Marks & Clerk
Turco Maria Caterina
LandOfFree
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