A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
A61M 25/10 (2006.01) A61M 37/00 (2006.01)
Patent
CA 2430024
An apparatus for delivery of biologically active materials comprises a catheter and balloon having micro-needles or pores. In the apparatus, the balloon can have a polymer coating containing the biologically active material, and the apparatus can include a sheath surrounding the balloon. In one embodiment the biologically active material is delivered through lumens in the micro-needles. Another embodiment of the invention is an apparatus for delivery of biologically active materials comprising a catheter with a balloon disposed thereon and a shockwave generator for producing a shockwave for delivering the biologically active material to a body lumen. Methods for delivery of biologically active materials are also disclosed.
L'invention concerne un dispositif d'administration de substances bioactives comprenant un cathéter et un ballonnet muni de micro-aiguilles ou de pores, ce ballonnet pouvant être recouvert d'un revêtement polymérique renfermant une substance bioactive. Ce dispositif peut également comprendre une gaine entourant ledit ballonnet. Dans un mode de réalisation, la substance bioactive est administrée par l'intermédiaire des lumières des micro-aiguilles. Dans un autre mode de réalisation, l'invention se rapporte à un dispositif d'administration de substances bioactives comprenant un cathéter muni d'un ballonnet disposé sur ce cathéter, ainsi qu'un générateur d'ondes de choc destiné à produire une onde de choc en vue d'administrer cette substance bioactive dans une lumière corporelle. L'invention porte enfin sur des méthodes d'administration de substances bioactives.
Herrmann Robert A.
Naimark Wendy
Palasis Maria
Osler Hoskin & Harcourt Llp
Scimed Life Systems Inc.
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