A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/159, 167/206
A61K 47/00 (2006.01) A61K 9/00 (2006.01) A61K 31/785 (2006.01) A61K 31/79 (2006.01) C08L 33/26 (2006.01) G02B 1/04 (2006.01)
Patent
CA 1039188
ABSTRACT OF THE DISCLOSURE A base for ophthalmological medicinal preparations consists of at least one polymer selected from a homopolymer of an amide of acrylic acid having a molecular weight from 30,000 to 1,000,000, and a copolymer of an amide of acrylic acid with unsaturated compounds from the group consisting of N-vinylpyrrol- idone, ethyl acrylate, butyl acrylate, N-vinylcaprolactam, vinyl acetate, the molecular weight of the copolymer being from 20,000 to 500,000, and containing from 10 to 90 per cent acrylamide links and an active principle selected from the group consisting of 3-ethyl-4(1-methyl-5-imidazolyl)-tetrahydrofuran-2-one, atropine, 3-methoxy-6-sulphanilamindopyridazine, .beta.-dimethylaminoethyl-p- butylaminobenzoate, neamine and 5-iodo-2-desoxyuridine. The ophthalmological medicinal film is an oblong plate, 6 - 9 mm long, 3 - 5 mm wide and 0.2 - 0.6 mm thick consisting of at least one polymer selected from a homopolymer of an amide of acrylic acid having a molecular weight from 30,000 to 1,000,000, and a copolymer of an amide of acrylic acid with unsaturated compounds, the molecular weight of the copolymer being from 20,000 to 500,000, and containing from 10 to 90 per cent acrylamide links and the active principle, viz., 3-ethyl-4-(1-methyl-5-imida- zolyl)-tetrahydrofuran-2-one or atropine, or 3-methoxy-6-sulphanil- amidopyridazine, or .beta.-dimethylamino-ethyl-p-butylaminobenzoate, or neamine, or ?-iodo-2-desoxyuridine. The ophthalmological medicinal film is used for treatment of glaucoma of various forms, thrombosis of the central vein of the retina, atrophy of the optic nerve, for dilating the pupil and paralysis of accommodation, in treatment of keratitis, iritis, iridocyclitis, ulcers of the cornea, trachoma, herpetic keratitis uveitis, and adenoviral infections, in extraction of foreign objects from the eye, and in various interventions in the organ of vision.
154458
Davydov Anatoly B.
Khromov Gennady L.
Maichuk Jury F.
Tishina Inna F.
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