C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/078 (2006.01) A61K 38/05 (2006.01) A61P 7/02 (2006.01) A61P 9/00 (2006.01) C07K 5/065 (2006.01)
Patent
CA 2538075
The invention relates to the novel base-substituted benzylamine analogs of general formula (I), wherein A represents P2--P1 with P1 = (A) and P2 = (B), for use as coagulation factor Xa inhibitors. The invention also relates to the production and use of said analogs in the therapy and prophylaxis of cardiovascular diseases and thromboembolic events.
L'invention concerne de nouvelles substances analogues à la benzylamine, à base substituée, de formule (I), en tant qu'inhibiteurs du facteur de coagulation Xa, leur réalisation et leur utilisation pour le traitement thérapeutique et prophylactique de maladies cardio-vasculaires et d'incidents thromboemboliques. (I), A étant P¿2?--P¿1?, sachant que P¿1?= (A) et P¿2?= (B).
Doennecke Daniel
Schweinitz Andrea
Steinmetzer Torsten
Stuerzebecher Anne
Stuerzebecher Joerg
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Curacyte Chemistry Gmbh
The Medicines Company (leipzig) Gmbh
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