Basic esters of benzoic acids and 2-thio- phencarboxylic...

Details Basic esters of benzoic acids and 2-thio- phencarboxylic... Basic esters of benzoic acids and 2-thio- phencarboxylic...

C - Chemistry, Metallurgy

07

D

260/474, 260/279

C07D 333/38 (2006.01) C07D 295/088 (2006.01) C07D 295/14 (2006.01)

Patent

CA 1244020

ABSTRACT OF THE DISCLOSURE The present invention provides novel basic esters of the formula I Image (1) wherein R is a group of the formulae Image or Image wherein R1 is hydrogen or C1-C4 alkyl, and R2 is C1-C4 alkyl, halogen, a C1-C4 alkoxy, C1-C4 alkylthio, nitro, amino or a C1-C4 alkylamino, R1 and R2 being the same or different, and R3 is a basic group selected from di(C1-C4)alkylamino or a 6-membered nitrogen containing aromatic heterocyclic group which may contain a further oxygen atom and to their pharmacologically useful salts with acids which are preferably used in local anaesthesia.

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