C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/283, 260/289
C07D 217/02 (2006.01) C07D 217/04 (2006.01) C07D 217/14 (2006.01) C07D 217/24 (2006.01)
Patent
CA 1076119
ABSTRACT OF THE DISCLOSURE Compounds of the formula (II) are disclosed Image (II) and salts thereof wherein R1 is a C1-6 alkyl, C3-6 cycloalkyl phenyl, napthyl, aralkyl, substituted phenyl or substituted napthyl group; R2 is a group: Image Image wherein R6 is a hydrogen atom or a C1-6 alkyl group, R7 is a hydrogen atom or a C1-6 alkyl, phenyl, tolyl, or benzyl group or R6 is linked to R7 so that the NR6R7 moiety is a 5-, 6- or 7- membered ring, R8 is a hydrogen atom or a C1-4 alkyl group or is joined to R6 to form part of a morpholino ring and R9 and R10 are each hydrogen atoms or C1-4 alkyl groups; R3 is a hydrogen atom or a C1-6 alkyl or a trifluoromethyl group; R4 is a hydrogen atom or a C1-6 alkyl, benzyl or phenyl group or an acyl group containing from 2 to 7 carbon atoms and R5 is hydrogen atom or a C1-6 alkyl group. The compounds have anorexic inducing and mood modifying activity. Methods of preparation are also disclosed.
258633
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