Basic formulations of quinolonecarboxylic acids

Details Basic formulations of quinolonecarboxylic acids Basic formulations of quinolonecarboxylic acids

A - Human Necessities

61

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A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 47/00 (2006.01) A61K 47/02 (2006.01)

Patent

CA 1273578

23189-6157 Abstract In the parenteral administration of a carboxylic acid of the formula Image Image in which X is N, C-H or C-F Z is O or CH2 R1 is hydrogen, methyl, ethyl or .beta.-hydroxyethyl, R2 is cyclopropyl, 2-fluoroethyl or ethyl, R3 is hydrogen or methyl, and R4 is H or methyl, the improvement which comprises administering the carboxylic acid in the form of a basic salt thereof. Surprisingly the basic salts are suitable and storage stable.

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