Basic oxazoline-amide derivatives of ge 2270 and ge...

C - Chemistry – Metallurgy – 07 – D

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C07D 513/22 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2212437

The present invention refers to basic oxazoline-amide derivatives of GE 2270 and GE 2270-like antibiotics of general formula (I), wherein the group GE represents the antibiotic core molecule. The amide derivatives of antibiotic GE 2270 of formula (I) are antimicrobial agents mainly active against gram positive bacteria.

L'invention porte sur des dérivés basiques oxazoline-amidés des antibiotiques GE 2270 ou similaires, de formule générale (I) dans laquelle le groupe GE représente la molécule du noyau de l'antibiotique. Les dérivés amidés de l'antibiotique GE 2270 de formule (I) sont des agents antimicrobiens principalement actifs contre les bactéries du type gram positif.

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