Basic proline-amide derivatives of ge 2270 and ge 2270-like...

Details Basic proline-amide derivatives of ge 2270 and ge 2270-like... Basic proline-amide derivatives of ge 2270 and ge 2270-like...

C - Chemistry, Metallurgy

07

D

C07D 513/22 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2212372

The present invention refers to basic amides derivatives of GE 2270 and GE 2270-like antibiotics of general formula (I), wherein the group GE represents the antibiotic core molecule. The amide derivatives of antibiotic GE 2270 of formula (I) are antimicrobial agents mainly active against gram positive bacteria.

L'invention porte sur des dérivés amidés basiques des antibiotiques GE 2270 (et leurs analogues) de formule générale (I) dans laquelle le groupe GE représente la molécule du noyau de l'antibiotique. Ces dérivés sont des agents antimicrobiens principalement actifs contre les bactéries Gram positif.

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