Basically alkylated dithiosalicylic acid amides, processes...

Details Basically alkylated dithiosalicylic acid amides, processes... Basically alkylated dithiosalicylic acid amides, processes...

C - Chemistry, Metallurgy

07

D

260/336, 260/306

C07D 207/08 (2006.01) C07D 207/09 (2006.01) C07D 211/26 (2006.01) C07D 211/34 (2006.01)

Patent

CA 1102321

Abstract of the Disclosure The invention provides novel antithrombotics diphenyl- disulphide-2,2'-bis-carboxylic acid amides of the general formula Image (I) in which R1 represents a hydrogen or halogen atom or an optionally substituted alkyl, alkoxy or aralkoxy group. R2 represents a hydrogen or halogen atom or an optionally substituted lkyl or alkoxy group, or together with R1, and adjacent carbon atoms of the benzenoid nucleus, forms an optionally substituted aliphatic or carbocyclic aromatic ring. R3 resents an optionally substituted alkyl group, A represents a single bond or an optionally substituted alkylene chain and m and n each represents 0 or a number from 1 to 5, m and n together having a value of 2-5, and acid addition salts thereof. Also included in the invention are compositions containing said antithrombotic compounds and methods for using said compounds or compositions for combating thrombo-embolic illness. In addition, the invention includes methods for the preparation of the antithrombotic compounds. -1a-

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