A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) A61K 39/21 (2006.01) A61P 31/00 (2006.01) A61P 31/18 (2006.01)
Patent
CA 2494359
A recombinant BCG vaccine transformed by an expression vector which carries a polynucleotide encoding a foreign antigenic protein characterized by being usable for priming in immune induction via twice or more antigenic stimulations; and an immune induction method characterized by comprising priming with the use of the above BCG vaccine and boostering once or more with the use of a non-BCG vaccine expressing the same antigenic protein.
L'invention concerne un vaccin BCG recombinant transformé par un vecteur d'expression qui contient un polynucléotide codant une protéine antigène étrangère caractérisée par le fait qu'elle est utilisée pour l'amorçage dans l'induction immune par au moins deux stimulations antigènes ; et un procédé d'induction immune caractérisé par le fait qu'il comprend l'amorçage au moyen du vaccin BCG susmentionné et au moins une injection de rappel un vaccin non BCG exprimant la même protéine antigène.
Balachandra Kruavon
Honda Mitsuo
Izumi Yasuyuki
Matsuo Kazuhiro
Promkhatkaew Duanthanorm
Department Of Medical Sciences Ministry Of Public Health Of Thailand
Japan As Represented By Director General Of National Institute O
Japan Science And Technology Agency
Norton Rose Or S.e.n.c.r.l.,s.r.l./llp
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