Bcl-2-selective apoptosis-inducing agents for the treatment...

Details Bcl-2-selective apoptosis-inducing agents for the treatment... Bcl-2-selective apoptosis-inducing agents for the treatment...

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) A61K 31/404 (2006.01) A61P 35/00 (2006.01) C07D 209/32 (2006.01) C07D 211/96 (2006.01) C07D 213/64 (2006.01) C07D 215/20 (2006.01) C07D 217/16 (2006.01) C07D 235/26 (2006.01) C07D 249/04 (2006.01) C07D 295/125 (2006.01) C07D 295/14 (2006.01) C07D 309/14 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2744711

Disclosed are compounds of formula (I) which inhibit the activity of anti- apoptotic BcI -2 or BcI -xL proteins, compositions containing the compounds and methods of treating diseases during which are expressed anti -aooptotic Bcl-2 protein.

L'invention porte sur des composés qui inhibent l'activité de protéines Bcl-2 ou Bcl-xL anti-apoptotiques, sur des compositions contenant les composés et sur des procédés de traitement de maladies pendant lesquelles sont exprimées des protéines Bcl-2 anti-apoptotiques.

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