Bcl2l12 polypeptide activators and inhibitors

Details Bcl2l12 polypeptide activators and inhibitors Bcl2l12 polypeptide activators and inhibitors

C - Chemistry, Metallurgy

12

N

C12N 5/10 (2006.01) A61K 31/7088 (2006.01) A61K 31/7105 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/37 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2523517

The invention provides methods and materials related to Bc12L12 polypeptides and the biological activities of Bc12L12 polypeptides. For example, the invention provides methods and materials related to identifying activators and inhibitors of Bc12L12 polypeptide activities such as the ability to block apoptosis and promote cell growth and transformation. The invention also provides methods and materials for treating mammals having cancer.

La présente invention concerne des techniques et des matériaux relatifs aux polypeptides Bc12L12 et aux activités biologiques de ces polypeptides Bc12L12. Cette invention concerne, par exemple, des techniques et des matériaux relatifs à l'identification d'activateurs et d'inhibiteurs des activités de polypeptides Bc12L12 telles que la capacité de bloquer l'apoptose et de favoriser la croissance et la transformation cellulaire. Cette invention concerne aussi des techniques et des matériaux destinés à traiter des mammifères atteints de cancer.

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