Bcr-complex-specific antibodies and methods of using same

Details Bcr-complex-specific antibodies and methods of using same Bcr-complex-specific antibodies and methods of using same

C - Chemistry, Metallurgy

07

K

C07K 16/46 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) A61P 37/02 (2006.01) C07K 16/28 (2006.01) C12N 15/13 (2006.01)

Patent

CA 2720365

This invention relates to chimeric and humanized antibodies that specifically bind the BCR complex, and particularly chimeric and humanized antibodies to the BCR complex. The invention also relates to methods of using the antibodies and compositions comprising them in the diagnosis, prognosis and therapy of diseases such as cancer, autoimmune diseases, inflammatory disorders, and infectious disease.

Cette invention concerne des anticorps chimériques et humanisés qui lient spécifiquement le complexe BCR, et en particulier des anticorps chimériques et humanisés contre le complexe BCR. L'invention concerne également des procédés d'utilisation des anticorps et des compositions les comprenant dans le diagnostic, le pronostic et le traitement de maladies comme le cancer, des maladies auto-immunes, des affections inflammatoires et des maladies infectieuses.

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