Benz(g) indoles and their use as spla2 inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 209/60 (2006.01) A61K 31/403 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2431506

A novel class of benz[g]indole compounds is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of Inflammatory Diseases such as septic shock.

L'invention concerne une nouvelle classe de composés benz[g]indole ainsi que l'utilisation de tels composés pour inhiber la libération d'acides gras effectuée par l'intermédiaire de sPLA2 pour traiter des maladies inflammatoires telles qu'un choc septique.

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