Benzamide and benzoate anti-hiv compounds

Details Benzamide and benzoate anti-hiv compounds Benzamide and benzoate anti-hiv compounds

A - Human Necessities

01

N

A01N 37/00 (2006.01) A01N 37/10 (2006.01) A01N 37/12 (2006.01) A01N 37/18 (2006.01) A01N 37/44 (2006.01) A61K 31/16 (2006.01) A61K 31/165 (2006.01) A61K 31/215 (2006.01) A61K 31/235 (2006.01) A61K 31/24 (2006.01)

Patent

CA 2559972

The invention provides a therapeutic method for preventing or treating a pathological condition or symptom in a mammal, such as a human, wherein the infectivity of a pathogen such as a retrovirus toward mammalian cells is implicated and inhibition of its infectivity is desired comprising administering to a mammal in need of such therapy, an effective amount of procaine, procainamide or an analog thereof that inhibits pathogenic infectivity, including pharmaceutically acceptable salts thereof.

L'invention concerne un procédé thérapeutique pour la prévention ou le traitement d'un état ou d'un symptôme pathologique chez un mammifère, tel qu'un être humain, pour lequel l'infectivité d'un pathogène tel qu'un rétrovirus à l'égard des cellules de mammifère est impliquée, et pour lequel l'inhibition de ladite infectivité est désirée. Le procédé consiste à administrer à un mammifère nécessitant un tel traitement, une quantité efficace de procaïne, procaïnamide ou un analogue de ces composés inhibant l'infectivité pathogène, y compris les sels pharmaceutiquement acceptables de ces composés.

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