C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
167/179, 260/279
C07C 233/77 (2006.01) A61K 31/165 (2006.01) A61K 31/18 (2006.01) A61K 31/33 (2006.01) C07C 231/02 (2006.01) C07C 255/50 (2006.01) C07C 311/15 (2006.01) C07D 295/08 (2006.01) C07D 295/092 (2006.01) C07D 295/14 (2006.01) C07D 317/68 (2006.01)
Patent
CA 1335101
Amide-compounds represented by the formula (I): Image (I) wherein R1 represents hydrogen, lower alkoxy, hydroxy, lower alkyl, halogen, amino which can be substituted by lower alkyl, nitro, cyano, sulfamoyl which can be substituted by lower alkyl, R2 represents hydrogen, lower alkoxy, hydroxy, lower alkyl, halogen, amino, nitro, wherein R1 and R2 can be combined to form methylenedioxy, R3 means hydrogen, lower alkyl, halogen, or amino, R4 and R5 may be the same or different and each represents lower alkyl or wherein R4 and R5 may be combined together with nitrogen to form 1-pyrrolidinyl or piperidino, and pharmacologically-acceptable acid-addition salts thereof, which exhibit excellent effects in the activation of gastric motor function, a process for preparation pharmaceutical compositons thereof, as well as a method for the treatment of a subject suffering from an ailment associated with inadequate gastric motor function by administrating such a compound to the said subject, are all disclosed.
576117
Itoh Yasuo
Kato Hideo
Koshinaka Eiichi
Nishino Hiroyuki
Ogawa Nobuo
Abbott Japan Co. Ltd.
Dennison Associates
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