Benzamide derivative, anti-ulcer drug, and antibacterial drug

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 295/155 (2006.01) A61K 31/445 (2006.01) C07D 295/135 (2006.01)

Patent

CA 2234139

A benzamide derivative or a salt thereof expressed by the following formula 1: Image wherein R1 is hydrogen atom or a lower alkyl group; R2 is a benzyl or an alkenyl group; and n is an integer of 1 to 6. The benzamide derivative or a salt thereof has an anti-ulcer effect or an antibacterial activity against Helicobacter pyroli, and has also high safety to be available for prevention or cure of ulcers.

Dérivé de benzamide ou sel de ce composé, exprimés par la formule suivante 1 Image , où R1 est un atome d'hydrogène ou un groupe alkyle inférieur, R2 est un groupe benzyle ou alcényle, et n est un entier de 1 à 6. Le dérivé de benzamide ou un sel de ce composé ont des propriétés antiulcéreuses ou une activité antibactérienne vis-à-vis d'Helicobacter pyroli; ils permettent également de prévenir ou de traiter de façon très sécuritaire les ulcères.

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