Benzamide derivatives

Details Benzamide derivatives Benzamide derivatives

C - Chemistry, Metallurgy

07

D

260/312, 260/304

C07D 257/06 (2006.01) C07C 45/40 (2006.01) C07C 45/67 (2006.01) C07C 49/835 (2006.01) C07C 49/86 (2006.01) C07C 65/05 (2006.01) C07C 65/21 (2006.01) C07C 65/24 (2006.01) C07C 65/30 (2006.01) C07C 65/40 (2006.01) C07C 205/56 (2006.01) C07C 205/61 (2006.01) C07D 257/04 (2006.01)

Patent

CA 1094565

ABSTRACT OF THE DISCLOSURE: The present invention relates to benzamide derivatives of the formula:- Image I wherein R1 represents a fluorine, chlorine or bromine atom, or an alkyl, alkoxy, alkylthio, alkylsulphonyl, alkanoylamino, alkylami- no or alkylsulphamoyl group, each such group containing from 1 to 6 carbon atoms, a dialkylsulphamoyl, dialkylamino or dialkylcarba- moyl group (wherein the two alkyl groups may be the same or dif- ferent and each contains from 1 to 4 carbon atoms), an alkanoyl, alkoxycarbonyl, alkoxycarbonylamino or alkylcarbamoyl group contain- ing from 2 to 6 carbon atoms, or a hydroxy, formyl, nitro, trifluo- romethyl, aryl, benzyloxycarbonylamino, amino, sulphamoyl, cyano, tetrazol-5-yl, carboxy, carbamoyl or aroyl group, and n represents an integer 1, 2 or 3, and to processes for their production. These derivatives are new compounds possessing pharmacological properties, in particular properties of value in the treatment of respiratory disorders manifested by the interaction of tissue-fixed antibodies with specific antigens.

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