Benzamide derivatives

C - Chemistry – Metallurgy – 07 – D

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260/315.25

C07D 233/61 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1195993

-48- ABSTRACT "BENZAMIDE DERIVATIVES" Benzamide derivatives of the general formula: Image I wherein A represents a divalent straight- or branched-chain alkylene group containing from 1 to 6 carbon atoms and R1 represents a halogen atom or a hydroxy, mercapto, amino, nitro, cyano, carboxy or carbamoyl group or an alkyl, fluorine substituted alkyl, alkoxy, alkylthio, alkyl- sulphinyl, alkylsulphonyl, alkoxycarbonyl, alkylamino, dialkylamino, alkylcarbamoyl, dialkylcarbamoyl, alkanoyl, alkanoyloxy or alkanoylamino group and m represents zero or the integer 1, 2 or 3, R2 represents a hydrogen atom or an alkyl group, R3 represents a halogen atom or a hydroxy, amino, nitro, cyano, carboxy or carbamoyl group or an alkyl, fluorine-substituted alkyl, alkoxy, alkoxy- carbonyl, dialkylamino, alkylcarbamoyl or alkanoylamino group and n represents zero or the integer 1 or 2, R4 represents an alkyl radical and p represents zero or the integer 1 or 2, or a pharmaceutically acceptable salt thereof, possess useful pharmacological properties.

435172

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