Benzamide derivatives

Details Benzamide derivatives Benzamide derivatives

C - Chemistry, Metallurgy

07

C

C07C 323/42 (2006.01) A61K 31/165 (2006.01) A61K 31/195 (2006.01) A61K 31/415 (2006.01) C07C 59/125 (2006.01) C07C 233/47 (2006.01) C07C 233/49 (2006.01) C07C 233/55 (2006.01) C07C 237/42 (2006.01) C07C 237/44 (2006.01) C07C 323/63 (2006.01) C07C 323/65 (2006.01) C07D 233/61 (2006.01) C07D 295/155 (2006.01)

Patent

CA 2089151

2089151 9203412 PCTABS00010 A benzamide derivative of formula (I) wherein R1 represents alkyl optionally containing one or more carbon-carbon double or triple bonds, and optionally interrupted by one or more hetero atoms, or sulphinyl or sulphonyl groups, optionally carrying one or more substituents selected from halogen, amino, alkoxy, alkylthio, alkylamino, or -CONR6R7 groups wherein R6 represents hydrogen or methyl and R7 represents methyl, trifluoromethyl or trichloromethyl, the symbols R2 represent hydrogen, alkyl or optionally substituted phenyl or the two groups R2 form a ring, R3 represents hydrogen or alkyl, R4 represents alkoxy, alkylthio, dimethylamino, or a 5- to 8-membered heterocyclo group, and R5 represents -NR8R9 or -OR10 wherein R8 and R9 represents hydrogen or alkyl optionally containing one or more carbon-carbon double or triple bonds, and optionally interrupted by one or more hetero atoms, or sulphinyl or sulphonyl groups, and R10 represents hydrogen or alkyl optionally containing one or more carbon-carbon double or triple bonds, and optionally interrupted by one or more hetero atoms, or sulphinyl or sulphonyl groups, and pharmaceutically acceptable salts thereof, possess useful pharmacological properties.

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