Benzamide derivatives as oxytocin agonists and vasopressin...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 487/04 (2006.01) A61K 31/5517 (2006.01) A61P 15/00 (2006.01) C07D 471/04 (2006.01) C07D 471/14 (2006.01) C07D 487/14 (2006.01) C07D 495/04 (2006.01) C07D 498/04 (2006.01)

Patent

CA 2513220

Novel compounds according to general formula 1, wherein Gl is NR5R6 or a fused polycyclic group that are specific OT receptor agonists and/or Vla receptor antagonists. Pharmaceutical compositions comprising such compounds are useful in the treatment of, inter alia, primary dysmenorrhoea.

L'invention concerne de nouveaux composés selon la formule générale (1) dans laquelle G?1¿ représente NR?5¿R?6¿ ou un groupe polycyclique fusionné lesquels sont des agonistes du recteur OT et/ou des antagonistes du récepteur V¿1a? spécifiques. L'invention concerne également des compostions pharmaceutiques contenant lesdits composés utiles dans le traitement, inter alia, de la dysménorrhée primaire.

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