Benzamide or phenylacetamide derivatives useful as thyroid...

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 235/52 (2006.01) A61K 31/195 (2006.01) A61P 5/16 (2006.01) C07C 235/34 (2006.01)

Patent

CA 2492046

This invention relates to novel compounds, which are thyroid receptor ligands, and to methods of preparing such compounds. In addition, a method is provided for preventing, inhibiting or treating diseases or disorders associated with metabolism dysfunction or which are dependent upon the expression of a T3 regulated gene, wherein a compound as described herein is administered in a therapeutically effective amount.

La présente invention concerne de nouveaux composés, qui sont des ligands de récepteurs de la thyroïde et des techniques de préparation de ces composés. Cette invention concerne aussi une technique de prévention, d'inhibition ou de traitement de maladies ou de pathologies associées à un dysfonctionnement du métabolisme ou dépendantes de l'expression d'un gène régulé T¿3?, un composé de cette invention étant administré en quantité thérapeutiquement efficace.

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