C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/75 (2006.01) A61K 31/44 (2006.01) A61K 31/4439 (2006.01) A61K 31/444 (2006.01) A61P 7/02 (2006.01) C07D 401/12 (2006.01)
Patent
CA 2401778
Benzamide compounds of the formulae (VI) and (VII), where the variables are as defined in the claims, including their pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivatives having activity against mammalian factor Xa are described. Compositions containing such compounds are also described. The compounds and compositions are useful in vitro or in vivo for preventing or treating coagulation disorders.
L'invention se rapporte à de nouveaux composés benzamides, et notamment à leurs isomères, sels, hydrates et dérivés de promédicaments pharmaceutiquement acceptables présentant une activité dirigée contre le facteur Xa mammalien. L'invention se rapporte également à des compositions contenant ces composés. Ces composés et compositions s'avèrent utiles <i>in vitro</i> ou <i>in vivo</i> pour prévenir ou traiter les troubles de la coagulation.
Goldman Erick
Huang Wenrong
Li Wenhao
Scarborough Robert
Song Yonghong
Cor Therapeutics Inc.
Fetherstonhaugh & Co.
Millennium Pharmaceuticals Inc.
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