C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/18 (2006.01) A61K 31/395 (2006.01) A61P 7/02 (2006.01) C07C 311/16 (2006.01) C07C 317/44 (2006.01) C07D 213/75 (2006.01) C07D 217/22 (2006.01) C07D 333/38 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2385592
Compounds of the formula A - Q - D - E - G - J - X in which D is a direct link, a substituted or unsubstituted phenyl or naphthyl group or a heterocyclic ring system; X is a substituted or unsubstituted phenyl or naphthyl group or a heterocyclic system; and the other variables are as defined in the claims, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.
La présente invention concerne des composés benzamidiques, leurs sels et des compositions correspondantes présentant une activité contre le facteur Xa mammalien. Ces composés convient in vitro ou in vivo pour la prévention ou le traitement des troubles de la coagulation.
Goldman Eric
Huang Wenrong
Li Wenhao
Scarborough Robert
Song Yonghong
Fetherstonhaugh & Co.
Millennium Pharmaceuticals Inc.
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