C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) A61K 31/55 (2006.01) A61K 31/675 (2006.01) C07D 233/26 (2006.01) C07D 233/64 (2006.01) C07D 239/06 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 453/02 (2006.01) C07F 9/6558 (2006.01)
Patent
CA 2245925
This invention is directed to benzamidine derivatives substituted by amino acid and hydroxy acid derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.
Cette invention se rapporte à des dérivés de benzamidine substitués par des dérivés amino acide et hydroxy acide qui s'avèrent utiles en tant qu'agents anticoagulants. Cette invention se rapporte également à des compositions pharmaceutiques contenant les composés décrits ci-dessus ainsi qu'à des procédés d'utilisation de ces composés permettant de traiter des états pathologiques caractérisés par une activité thrombotique.
Kochanny Monica
Mohan Raju
Morrissey Michael M.
Ng Howard P.
Yun Weiya
Bereskin & Parr
Berlex Laboratories Inc.
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