C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 307/52 (2006.01) A61K 31/34 (2006.01) A61K 31/381 (2006.01) A61P 31/00 (2006.01) C07D 333/20 (2006.01)
Patent
CA 2549534
A method of treating Pneumocystis carinii pneumonia in a subject in need of such treatment is disclosed. The method comprises orally administering to the subject a bis- benzamidoxime, or a pharmaceutically acceptable salt thereof, that is reduced in the subject to produce a benzamidine having anti-P. carinii activity. The method of the present invention may alternatively comprise intravenously administering to the subject an active compound as disclosed herein. Pharmaceutical formulations and active compounds useful in the practice of the present invention are also disclosed.
Boykin David Withers
Hall James Edwin
Tidwell Richard Ray
Georgia State University
Sim & Mcburney
The University Of North Carolina At Chapel Hill
University Of North Carolina At Chapel Hill
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