C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 223/16 (2006.01) A61K 31/55 (2006.01) C07D 267/02 (2006.01) C07D 281/02 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2172354
Compounds with neutral endopeptidase (NEP) inhibitory activity corresponding to the formula I Image I in which R1 is a lower alkoxy-lower-alkyl group whose lower alkoxy radical is substituted by a lower alkoxy group, or a phenyl-lower-alkyl or phenyloxy-lower-alkyl group which can optionally be substituted in the phenyl ring by lower alkyl, lower alkoxy or halogen, or a naphthyl-lower-alkyl group, A is CH2, O or S, R2 is hydrogen or halogen, R3 is hydrogen or halogen, R4 is hydrogen or a group forming a biolabile ester, and R5 is hydrogen or a group forming a biolabile ester, and the physiologically acceptable acid addition salts thereof.
Antel Jochen
Hoeltje Dagmar
Messinger Josef
Thormaehlen Dirk
Waldeck Harald
Antel Jochen
Hoeltje Dagmar
Messinger Josef
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Solvay Pharmaceuticals Gmbh
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