C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 223/16 (2006.01) A61K 31/55 (2006.01) C07D 401/00 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/00 (2006.01) C07D 403/06 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/00 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/00 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 453/02 (2006.01) C07D 471/08 (2006.01) C07D 521/00 (2006.01) C07F 7/10 (2006.01)
Patent
CA 2170373
Benzazepine derivatives represented by the following general formula (I) useful as arginine vasopressin antagonists or pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and difluorobenzazepinone derivatives represented by the following general formulae (II) and (III) which are useful as production intermediates of the compound (I). (I) Image Image (II) Image (III)
L'invention concerne un dérivé de la benzazépine, représenté par la formule générale (I). Il est utilisable comme antagoniste de la vasopressine arginine. L'invention concerne également un sel de la benzazépine admis en pharmacie, et les dérivés de la difluorobenzazépinone représentés par les formules générales (II) et (III), ces deux derniers produits étant utilisés comme intermédiaires dans la production du composé (I).
Koshio Hiroyuki
Matsuhisa Akira
Sakamoto Ken-Ichiro
Tanaka Akihiro
Taniguchi Nobuaki
Dennison Associates
Yamanouchi Pharmaceutical Co. Ltd.
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