Benzazole derivatives, compositions, and methods of use as...

Details Benzazole derivatives, compositions, and methods of use as... Benzazole derivatives, compositions, and methods of use as...

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/4184 (2006.01) A61K 31/4725 (2006.01) C07D 401/12 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2759162

The present invention is directed to benzazole compounds that inhibit .beta.- site amyloid precursor protein-cleaving enzyme (BACE) and that may be useful in the treatment or prevention of diseases in which BACE is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which BACE is involved.

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