Benzene fused heterocyclic derivatives and application thereof

Details Benzene fused heterocyclic derivatives and application thereof Benzene fused heterocyclic derivatives and application thereof

C - Chemistry, Metallurgy

07

D

C07D 215/20 (2006.01) A61K 31/34 (2006.01) A61K 31/47 (2006.01) A61K 31/535 (2006.01) A61K 31/55 (2006.01) C07D 223/16 (2006.01) C07D 265/36 (2006.01) C07D 307/86 (2006.01)

Patent

CA 2305687

Fused benzene heterocycle derivatives represented by general formula (I) and TXA2 receptor antagonists containing the same as the active ingredient. Because of having a potent TXA2 receptor antagonism and a PGI2 receptor antagonism, these compounds are useful in treating or preventing diseases in which TXA2 participates.

Cette invention porte sur des dérivés hétérocycliques de benzène en fusion représentés par la formule générale (I) et sur des antagonistes du récepteur TXA¿2? contenant ces dérivés agissant comme ingrédient actif. Du fait que ces composés possèdent un puissant antagonisme du récepteur TXA¿2? et un puissant antagonisme du récepteur PGI¿2?, ils peuvent être utilisés dans le traitement ou la prévention de pathologies où intervient TXA¿2?.

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