Benzene, pyridine and pyrimidine derivative

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 233/61 (2006.01) A61K 31/17 (2006.01) A61K 31/395 (2006.01) C07C 275/40 (2006.01) C07D 211/14 (2006.01) C07D 211/34 (2006.01) C07D 233/54 (2006.01) C07D 233/64 (2006.01) C07D 233/68 (2006.01) C07D 233/90 (2006.01) C07D 235/02 (2006.01) C07D 235/12 (2006.01) C07D 235/14 (2006.01) C07D 249/00 (2006.01) C07D 249/06 (2006.01) C07D 249/18 (2006.01) C07D 257/04 (2006.01) C07D 295/092 (2006.01) C07D 295/155 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2052191

ABSTRACT OF THE DISCLOSURE A novel benzene, pyridine or pyrimidine derivative, useful as an anti-arteriosclerotic agent having the general formula shown below: Image (I) wherein R1 stands for a hydrogen or halogen atom, a lower alkyl, lower alkoxy, nitro or cyano group, or an amino group which may be substituted; R2 stands, in particular, for a group represented by the formula: Image (wherein R16 stands, by way of example, for an alkyl group having 1 to 6 carbon atoms; R3 stands, in particular, for a group represented by the formula: -O- (CH2)m-Y (wherein Y stands, by way of example, for an imidazolyl or piperazinyl group, and m is 1 to 6); R5 stands, in particular, for a hydrogen atom or a lower alkyl group; A stands for a group represented by the formula: Image wherein R6 stands, by way of example, for a hydrogen atom, a lower alkyl group, -N=,; and B stands for a group represented by the formula: Image wherein R4 stands, by way of example, for a hydrogen or a -N= group.

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