Benzenesulphonate salt of a morpholine urea derivative for...

A - Human Necessities – 61 – K

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A61K 31/5377 (2006.01) A61P 11/06 (2006.01) A61P 29/00 (2006.01) C07D 209/48 (2006.01) C07D 265/30 (2006.01) C07D 413/06 (2006.01)

Patent

CA 2479912

Compounds of formula (I), wherein A- represents the benzenesulphonate (besylate) anion; R represents H or C1-6 alkyl; and n is a number from 0.8 to 2.2 are CCR3 antagonists and are therefore indicated to be useful in therapy of inflammatory conditions.

L'invention concerne des composés de formule (I), dans laquelle A?-¿ représente l'anion benzènesulfonate (bésylate); R représente H ou alkyle C¿1-6?; et n représente un nombre entier compris entre 0,8 et 2,2 . Ces composés sont antagonistes de CCR3 est sont donc indiqués pour être utilisés dans la thérapie d'états inflammatoires.

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