C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/26 (2006.01) C07D 213/26 (2006.01)
Patent
CA 2629836
The present invention relates to salts of Formula (I) and to methods of manufacture thereof: where X is an organic or inorganic moiety, n is 0, 1. 2, 3 or 4; and R* and Rb are each independently selected from H. OH, C1, C2, C3 or C4 alkyl, C1, C2, C3 or C4 haloalkyl, C1, C2, C3 or C4 alkoxy, C1, C2, C3 or C4 alkenyl, or are both oxygen to produce the moiety NO2; and R1 is C1, C2, C3 or C4 alkyl; and Y and Z are both carbon; and the broken lines - represent saturated or unsaturated bonds. Salts of formula (I) may be intermediates in the process of forming cinnamanilide (Y). where R8 is selected from H, OH, C1, C2, C3 or C4 alkyl; and R1 is C1, C2, C3 or C4 alkyl.
La présente invention concerne des sels de composés aryles tels que décrits ci-après et des procédés de production de ces derniers, ainsi que d'autres substances. Plus particulièrement, l'invention concerne des sels utiles en tant qu'intermédiaires pour la synthèse du cinnamanilide représenté par la formule (Y), dans laquelle Ra est sélectionné parmi H, OH, alkyle C1, C2, C3 ou C4; et R1 représente alkyle C1, C2, C3 ou C4.
Girgis Michael J.
Hu Bin
Liu Yugang
Prashad Mahavir
Schaefer Frank
Fetherstonhaugh & Co.
Novartis Ag
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