Benzhydryl derivatives having calmodulin inhibitor properties

Details Benzhydryl derivatives having calmodulin inhibitor properties Benzhydryl derivatives having calmodulin inhibitor properties

C - Chemistry, Metallurgy

07

C

C07C 323/29 (2006.01) A61K 31/135 (2006.01) C07C 211/27 (2006.01) C07C 211/28 (2006.01) C07C 217/10 (2006.01) C07C 217/26 (2006.01) C07C 323/25 (2006.01)

Patent

CA 2046005

Abstract The invention relates to a benzhydryl derivative having the formula Image (I) wherein each of the groups R1, R2, and R3 represents one to four substituents independently selected from the group consisting of hydrogen, lower alkyl, halogen, and CF3, and at least one of the groups R1, R2, and R3 is halogen or CF3; R4 represents hydrogen or methyl; n is 2, 3, or 4; m is 1, 2, or 3; and X represents O or S; or its pharmaceutically acceptable salts. The benzhydryl derivative of the invention can be used to treat patients who are suffering from diseases which are influenced by calmodulin.

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