Benzhydrylamine derivatives

Details Benzhydrylamine derivatives Benzhydrylamine derivatives

C - Chemistry, Metallurgy

07

C

530/1.1, 260/515

C07C 229/34 (2006.01) C07C 59/90 (2006.01) C07C 251/40 (2006.01) C07C 271/22 (2006.01) C07K 1/00 (2006.01) C07K 1/04 (2006.01)

Patent

CA 1341257

Novel benzhydrylamine derivatives represented by general formulas (I) and (II) are useful as reaction reagents for the solid-phase synthesis of polypeptide amides making use of 9-fluorenylmethyloxycarbonyl group ("Fmoc"). An intermediate for these derivatives represented by the general formula (III) is also disclosed: (see formula I) (see formula II) (see formula III) where R1 and R2 each independently represents a C1-3 lower alkyl; n is an integer of 1-4; ~ is 1 or 2; and m is 1 or 2.

592310

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