Benzhydryloxy-alkylamine derivatives and process for the...

C - Chemistry – Metallurgy – 07 – D

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260/283, 260/241

C07D 217/04 (2006.01) C07D 295/08 (2006.01) C07D 295/088 (2006.01)

Patent

CA 1044230

ABSTRACT OF THE DISCLOSURE Benzhydryloxy-alkylamine derivatives of the general for- mula: Image (I) wherein X represents a halogen atom, a methyl or a methoxy group, A represents, together with the nitrogen atom to which it is attached, a hexamethyleneimino,heptamethyleneimino, 1, 2, 3, 4-tetrahydro-2-isoquinolyl or 1, 2, 3, 4-tetrahydro-6,7- dimethoxy-2-isoquinolyl group,and n is an integer having the value of 2, 3, or 4, and the pharmaceutically acceptable acid addition salts thereof. These compounds have prolonged anti- histaminic effect. And, a process for preparing the above compound.

229908

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