Benzimidazo[4,5-f]isoquinolinone derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 471/14 (2006.01) A61K 31/407 (2006.01) A61K 31/444 (2006.01) A61K 31/4545 (2006.01) A61K 31/4745 (2006.01) C07D 215/22 (2006.01) C07D 401/14 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2455181

Benzimidazo[4,5-f]isoquinolinone derivatives are inhibitors of Janus protein tyrosine kinases (Jak), and as such are useful as immunosuppressants, and in the treatment of diseases including asthma, allergies, autoimmune diseases .

L'invention porte sur des dérivés de la benzimidazo[4,5-f]isoquinolinone inhibiteurs des proteines tyrosine kinases Janus (Jak), qui peuvent servir d'immunosuppresseurs s'avérant utiles pour le traitement de maladies dont l'asthme, les allergies, et les maladies auto-immunes.

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