C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/14 (2006.01) A61K 31/407 (2006.01) A61K 31/444 (2006.01) A61K 31/4545 (2006.01) A61K 31/4745 (2006.01) C07D 215/22 (2006.01) C07D 401/14 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2455181
Benzimidazo[4,5-f]isoquinolinone derivatives are inhibitors of Janus protein tyrosine kinases (Jak), and as such are useful as immunosuppressants, and in the treatment of diseases including asthma, allergies, autoimmune diseases .
L'invention porte sur des dérivés de la benzimidazo[4,5-f]isoquinolinone inhibiteurs des proteines tyrosine kinases Janus (Jak), qui peuvent servir d'immunosuppresseurs s'avérant utiles pour le traitement de maladies dont l'asthme, les allergies, et les maladies auto-immunes.
Cubbon Rose M.
Cummings Richard T.
Goulet Joung L.
Hong Xingfang
Sinclair Peter J.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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