Benzimidazol derivatives modulate chemokine receptors

Details Benzimidazol derivatives modulate chemokine receptors Benzimidazol derivatives modulate chemokine receptors

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/404 (2006.01) A61K 31/423 (2006.01) A61K 31/4523 (2006.01) A61P 11/00 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) C07D 401/14 (2006.01) C07D 413/04 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2442268

The invention provides compounds of general formula (I) wherein A, X, m, R1, N, R2, Z1, Z2, Q, R3, R4, R5, R6, R7, R8, t and R16 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.

L'invention concerne des composés correspondant à la formule générale (I), dans laquelle A, X, m, R?1¿, N, R?2¿, Z?1¿, Z?2¿, Q, R?3¿, R?4¿, R?5¿, R?6¿, R?7¿, R?8¿, t et R?16¿ sont définis dans la spécification, ainsi que des procédés de préparation, des compositions pharmaceutiques les contenant et leur utilisation en thérapie.

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