Benzimidazole carbamites

Details Benzimidazole carbamites Benzimidazole carbamites

C - Chemistry, Metallurgy

07

D

C07D 235/32 (2006.01) A01N 43/52 (2006.01) A01N 43/72 (2006.01) A61K 31/41 (2006.01) A61K 31/47 (2006.01) C07D 401/04 (2006.01) C07D 403/02 (2006.01) C07D 403/04 (2006.01) C07D 405/04 (2006.01) C07D 413/04 (2006.01) C07D 417/02 (2006.01) C07D 417/04 (2006.01) C07D 417/06 (2006.01) C07D 417/12 (2006.01) C07J 43/00 (2006.01)

Patent

CA 2130665

Benzimidazole anthelmintic agents of formula (I) and their non-toxic salts in which R is H, CO2(C1-C10 alkyl), -CO2 (cholester-3-yl) or -CO2(CH2)COOH or -CO2(CH2)nCO2(C1-C6 alkyl), n = 1 to 10, R1 is optionally substituted benzoyl, phenyloxy, phenylthio, phenylsulfonyl, phenylsulfinyl, phenylsulfonyloxy, alkylthio, alkylsulfinyl, alkylsulfonyl, cycloalkylcarbonyl or is selected from a variety of heterocyclic groups and R2 and R3 are independently -CO2(C1-C4 alkyl).

Agents anthelmintiques de type benzimidazole de formule (I) et leurs sels non toxiques dans lesquels R est H, CO2(alkyle de type C1-C10), -CO2 (cholester-3-yle) ou -CO2(CH2)COOH ou -CO2(CH2)nCO2(alkyle de type C1-C6), n = 1 à 10, R1 peut être un groupe substitué benzoyle, phényloxy, phénylthio, phénylsulfonyle, phénylsulfinyle, phénylsulfonyloxy, alkylthio, alkylsulfinyle, alkylsulfonyle, cycloalkylcarbonyle ou est choisi parmi divers groupes hétérocycliques, et R2 et R3 sont, de façon indépendante, des groupes -CO2(alkyle de type C1-C4).

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