C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 235/18 (2006.01) A61K 31/4184 (2006.01) A61K 31/4439 (2006.01) A61K 45/06 (2006.01) A61P 11/06 (2006.01) A61P 35/00 (2006.01) A61P 37/08 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01)
Patent
CA 2441177
The present invention is directed to small molecule inhibitors of the IgE response to allergens, which are useful in the treatment of allergy and/or asthma or any diseases where IgE is pathogenic. This invention also relates to benzimidazole molecules that are cellular proliferation inhibitors and thus are useful as anticancer agents.
L'invention porte sur de petites molécules de formule I-III inhibitrices de la réponse de l'IgE aux allergies s'avérant utiles pour le traitement des allergies et/ou de l'asthme ou de tout syndrome où l'IgE est pathogène. L'invention porte également sur des molécules de benzimidazole inhibitrices de la prolifération cellulaire et pouvant donc servir d'agents anticancéreux.
Major Michael W.
Richards Mark L.
Sircar Jagadish C.
Avanir Pharmaceuticals
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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