Benzimidazole cyclooxygenase-2-inhibitors

Details Benzimidazole cyclooxygenase-2-inhibitors Benzimidazole cyclooxygenase-2-inhibitors

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/505 (2006.01) A61K 31/53 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2261426

This invention provides a compound of the following formula: (see fig. I) or the pharmaceutically acceptable salts thereof, preferably wherein Ar is heteroaryl; X1 and X2 are independently selected from halo, C1-C4 alkyl, hydroxy, C1-C4 alkoxy, amino, C1-C4 alkanoyl, carboxy, carbamoyl, cyano, nitro, mercapto, (C1-C4 alkyl)thio, (C1-C4 alkyl)sulfinyl, (C1-C4 alkyl)sulfonyl, aminosulfonyl, or the like; R1 is selected from hydrogen, straight or branched C1-C4 alkyl, C3-C8 cycloalkyl, C4-C8 cycloalkenyl, phenyl , heteroaryl and the like; R2 and R3 are independently selected from hydrogen, halo, C1-C4 alkyl, phenyl and the like; or R1 and R2 can form, together with the carbon atom to which they are attached, a C5-C7 cycloalkyl ring; and m and n are independently 0, 1, 2 or 3. These compounds and pharmaceutical compositions containing such compounds are useful as analgesics and anti-inflammatory agents.

Affiliated with

Also associated with

Rating

Benzimidazole cyclooxygenase-2-inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Benzimidazole cyclooxygenase-2-inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Benzimidazole cyclooxygenase-2-inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1471424