C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 235/06 (2006.01) A61K 31/4184 (2006.01) C07D 235/26 (2006.01)
Patent
CA 2539766
The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to benzimidazole containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with dysregulation of histone deacetylase (HDAC).
La présente invention concerne des composés hydroxamate, qui sont des inhibiteurs de l'histone déacetylase. L'invention concerne plus particulièrement des composés contenant du benzimidazole et leurs procédés de fabrication. Ces composés peuvent convenir comme médicaments pour le traitement de troubles prolifératifs ainsi que d'autres pathologies impliquant ou concernant une dysrégulation de l'histone déacetylase, ou bien étant associées à une telle dysrégulation.
Chen Dizhong
Deng Weiping
Sangthongpitag Kanda
Song Hong Yan
Sun Eric T.
S*bio Pte Ltd
Sim & Mcburney
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