Benzimidazole derivative and use as an angiotensin ii...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 413/00 (2006.01)

Patent

CA 2557538

The present invention relates to a compound represented by the formula (I) wherein R1 is a group represented by the formula wherein R2, R3, R4, R5, R6, R7 and R8 are each independently a hydrogen atom or a C6 - 1 alkyl, or a salt thereof. The compound of the present invention is useful as an agent for the prophylaxis or treatment of circulatory diseases such as hypertension and the like and metabolic diseases such as diabetes and the like.

La présente invention concerne un composé représenté par la formule (I) dans laquelle R<SUP>1</SUP> est un groupe représenté par la formule dans laquelle R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>6</SUP>, R<SUP>7</SUP> et R<SUP>8</SUP> sont chacun indépendamment un atome d'hydrogène ou un groupe alkyle en C<SUB>6-1</SUB>, ou un sel de celui-ci. Le composé de la présente invention est utile comme agent pour la prophylaxie ou le traitement de maladies circulatoires telles que l'hypertension et ses équivalents et de maladies métaboliques telles que le diabète et ses équivalents.

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