Benzimidazole derivative and use as angiotensin ii antagonist

Details Benzimidazole derivative and use as angiotensin ii antagonist Benzimidazole derivative and use as angiotensin ii antagonist

C - Chemistry, Metallurgy

07

D

C07D 413/10 (2006.01) A61K 31/4245 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2602624

The present invention provides (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 2- cyclopropyl-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4- yl]methyl}-1H-benzimidazole-7-carboxylate represented by the formula: which has superior properties as a pharmaceutical agent, a salt thereof, a crystal thereof, a pharmaceutical agent containing the compound, and the like.

L'invention se réfère au composé (5-méthyl-2-oxo-1,3-dioxol-4-yl)méthyl 2-cyclopropyl-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphényl-4-yl]méthyl}-1H-benzimidazole-7-carboxylate représenté par la formule (1), qui possède des propriétés supérieures comme agent pharmaceutique, à un sel de ce composé, à un cristal de celui-ci, à un agent pharmaceutique contenant ledit composé et analogue.

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