Benzimidazole derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 235/06 (2006.01) A61K 31/415 (2006.01) C07D 235/08 (2006.01)

Patent

CA 2207348

Disclosed are benzimidazole derivatives having the formula: (see fig. I) wherein, preferably, B is diethylmethyl, Y is hydrogen or methyl, R1 is ethyl, methyl or chloro and R2, R3 and R4 are each methyl. These compounds and their pharmaceutically acceptable salts are useful in the treatment of CNS and stress related disorders.

L'invention porte sur des dérivés du benzimidazole possédant la formule (voir fig. I), dans laquelle, de préférence, B est un groupe diéthylméthyle, Y est un atome d'hydrogène ou un groupe méthyle, R1 est un groupe éthyle, méthyle ou chloro et R2, R3 et R4 sont des groupes méthyle. Ces composés et leurs sels acceptables du point de vue pharmaceutique sont utiles dans le traitement du système nerveux central et de troubles liés au stress.

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