Benzimidazole derivatives and their use as gnrh antagonists

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 235/28 (2006.01) C07D 235/30 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 413/12 (2006.01) C07D 417/06 (2006.01) C07D 471/04 (2006.01) C07D 471/10 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2471044

The invention concerns novel benzimidazole derivatives of formula (I), wherein: A, Y, R¿1?, R¿2?, R¿3? and R¿4? represent diverse variable groups. Said products have a GnRH (Gonadotropin-Releasing Hormone) antagonist activity. The invention also concerns pharmaceutical compositions containing said products for preparing a medicine.

La présente demande a pour objet de nouveaux dérivés de benzimidazoles de formule (I) dans laquelle A, Y, R1, R2, R3, et R4 représentent divers groupes variables. Ces produits possèdent une activité antagoniste de la GnRH (Gonadotropin-Releasing Hormone). L'invention concerne également des compositions pharmaceutiques contenant lesdits produits et leur utilisation pour la préparation d'un médicament.

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