Benzimidazole derivatives and their use as vanilloid...

Details Benzimidazole derivatives and their use as vanilloid... Benzimidazole derivatives and their use as vanilloid...

C - Chemistry, Metallurgy

07

D

C07D 235/30 (2006.01) A61K 31/4184 (2006.01) A61K 31/4439 (2006.01) A61K 31/454 (2006.01) A61K 31/496 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2501539

Compounds of formula (I) are useful in the treatment of vanilloid-receptor- meditated diseases, such as inflammatory or neuropathic pain and diseases involving sensory nerve function such as asthma, rheumatoid arthritis, osteoarthritis, inflammatory bowel disorders, urinary incontinence, migraine and psoriasis.

L'invention concerne des composés représentés par la formule (I) utilisés dans le traitement de maladies induites par le récepteur vanilloïde, telles que la douleur inflammatoire ou neuropathique, ainsi que des maladies impliquant la fonction du nerf sensoriel, telles que l'asthme, la polyarthrite rhumatoïde, l'ostéoarthrose, les troubles du colon irritable, l'incontinence, la migraine et le psoriasis.

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