Benzimidazole derivatives and their use for modulating the...

C - Chemistry – Metallurgy – 07 – D

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C07D 235/06 (2006.01) A61K 31/4184 (2006.01)

Patent

CA 2632395

This invention relates to novel benzimidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.

La présente invention concerne de nouveaux dérivés de benzimidazole, des compositions pharmaceutiques qui les comprennent et des procédés de traitement les utilisant. Les composés de l~invention sont utiles pour traiter des maladies et des troubles du système nerveux central, lesquels répondent à la modulation du complexe du récepteur GABAA, et en particulier pour combattre l~anxiété et les maladies apparentées.

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