Benzimidazole derivatives and their use for modulating the...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 403/10 (2006.01) A61K 31/4184 (2006.01) A61K 31/42 (2006.01) A61K 31/427 (2006.01) A61P 25/00 (2006.01) C07D 405/10 (2006.01) C07D 409/10 (2006.01) C07D 413/10 (2006.01) C07D 417/10 (2006.01)

Patent

CA 2520281

This invention relates to novel benzimidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.

L'invention concerne de nouveaux dérivés de benzimidazole, des compositions pharmaceutiques contenant ces composés, et des méthodes de traitement associées. Les composés de l'invention sont utiles dans le traitement de maladies et de troubles du système nerveux central réagissant à une modulation du complexe du récepteur GABA<SB>A</SB>, et en particulier, utiles pour combattre l'anxiété et les maladies associées à l'anxiété.

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